Trans youth will no longer be prescribed puberty blockers at NHS England gender identity clinics in a new “blow” to gender-affirming healthcare.

Puberty blockers are a type of medicine that prevent puberty from starting by blocking the hormones – like testosterone and oestrogen – that lead to puberty-related changes in the body. In the case of trans youth, this can delay unwanted physical changes like menstruation, breast growth, voice changes or facial hair growth.

On Tuesday (12 March), NHS England confirmed the medicine, which has been described as “life-saving” medical care for trans youth, will only be available to young people as part of clinical research trials.

The government described the move as a “landmark decision”, Sky News reported. It believed such a move is in the “best interests of the child”.

  • @Tattorack@lemmy.world
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    -141 year ago

    We know so little about the actual process of gender dysphoria. Hormone blockers don’t solve or fix anything, but have been used simply because it’s the only thing that does something. Essentially bringing a blunt instrument to the problem.

    Considering the harmful nature of hormone blockers, I’m for not prescribing puberty blockers to youth. However, only so long as more research is put into it.

    • @jordanlund@lemmy.worldM
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      11 year ago

      Hormone blockers are generally used because it’s far easier for people to transition if they haven’t already been smacked around by puberty and it ends up giving a healthier result.

      https://www.texastribune.org/2023/03/24/texas-transgender-kids-transition-related-health-care/

      (I KNOW, right? “Texas Tribune?”)

      "Studies have found that transgender youth who take puberty blockers are significantly less likely to experience lifelong suicidal ideation than those who want the care and don’t get it. And studies show psychological trauma is reduced and life satisfaction increases when people who want transition-related hormone therapy get it.

      Major medical associations support transition-related care. They include the American Academy of Pediatrics, the American Medical Association, the Endocrine Society, the World Medical Association and the World Professional Association for Transgender Health."

    • @frezik@midwest.social
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      431 year ago

      GnRH was discovered in 1971, and has been available since the '80s. We have a pretty good idea of their long term effects. There could be more about effects on transgender youth in particular, but everything done so far shows it’s safe.

      • @Jax@sh.itjust.works
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        131 year ago

        I’m reading about migraines, joint pain, hot flashes/sweating, decreased libido (which I would expect to take place during treatment) persisting for months after discontinuing use of GnRH. I’m also reading that it can worsen diabetes and osteoporosis?

        Idk, to say that it’s without risk is false I think.

        • Aurelian
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          101 year ago

          How many of these side effects could just be the result of starting puberty after stopping the medication?

          • @Jax@sh.itjust.works
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            1 year ago

            I genuinely don’t know, but is osteoporosis common as a result of puberty?

            Edit:

            later puberty was linked to lower bone mineral density, and that both are risk factors for osteoporosis

            • Aurelian
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              81 year ago

              Also a risk when taking birth control, the question is how severe and can you recover after completing puberty.

                • Aurelian
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                  81 year ago

                  Ah I was referring to it as a side effect of birth control in adults. But birth control for ones that have gone through puberty is definitely better than the possibly deadly side effects of child birth and pregnancy.

        • @Icaria@lemmy.world
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          211 year ago

          Do yourself a favour and don’t read the possible side effects on the back of the box of paracetamol you bought from the supermarket.

        • SeaJ
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          271 year ago

          Safe does not mean no side effects. Those first things would still absolutely qualify it as safe. Those last two you mention seem to be inconclusive by the way you worded it.

          • @Jax@sh.itjust.works
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            11 year ago

            I word it this way because I’m not an expert, I was reading through a few studies I found on Google and am no way qualified to weigh in on this beyond a cursory glance.

            That being said, I’ve heard migraines be described similarly to torture. We can agree to disagree as to whether or not that’s safe (the effects of chronic pain are well documented).

            Also

            Prolonged treatment with Gonadotropin-Releasing Hormone (GnRH) agonists is known to induce bone loss among prostate cancer patients. However, evidence on the skeletal effects of GnRH antagonists is relatively less well-known. This review aims to examine the effects of GnRH antagonists on bone health. GnRH antagonists are an effective treatment for hormone-dependent conditions, such as advanced prostate cancer and endometriosis. They induce a competitive and reversible GnRH-receptor blockage, thereby suppressing the release of gonadotropins and sex hormones. The sex hormone ablation results in undesirable side effects, including accelerated bone loss. In animal studies, treatment with GnRH antagonists is reported to cause deterioration of bone microstructure. Human clinical trials revealed significant bone loss at the spine, hip and femur in patients treated with GnRH antagonists. Thus, osteoporosis and the resultant fragility fractures pose a significant impact on health and quality of life of GnRH antagonist users. Thus, early preventive measures of bone loss are critical in preventing fractures and its associated morbidity in these patients.

            The abstract from this https://www.eurekaselect.com/article/112477

            There are certainly other factors to consider, GnRH is used to treat prostate cancer if I’m not mistaken. I have no idea what would happen in an AFAB, and truth be told I’m not going that deep. I don’t think anyone should be telling anyone what they can or can’t put in/do with their bodies, but I’m not sure what to believe about the risk. Reading this would certainly make me second guess taking them considering my family history of arthritis.

            🤷‍♂️ idk mane

            • prole
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              1 year ago

              Yeah, you don’t know… It’s really not what it seems though, and it’s not actually about starting with a conclusion (we shouldn’t be treating trans kids) and then only glomming onto whatever scraps you can find that might indicate that your worldview is correct, while simply ignoring that mountains of evidence to the contrary.

              Definitely not that. You’re just asking questions! And it’s just a coincidence that every time someone tells you why you’re wrong, or asks you for more detail about your arguments, you resort to the whole, “I don’t know, I’m not an expert.” Yeah no shit.

              • @Jax@sh.itjust.works
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                1 year ago

                So you just didn’t read the part where I said “we shouldn’t be telling people what they can or can’t put in their bodies”, huh?

                My advice to you is to stop letting your emotions dictate your words.

                Edit: oh yeah, after re-reading what I wrote you definitely rage typed this response. Do better.

      • Jojo
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        11 year ago

        Um, excuse me, who said 40 years was long enough? If we don’t have trials that show how people receiving these drugs turned out all the way until they died then we don’t really have long term trials, do we?

        /s

        It’s such a fucking cop out. Nothing will ever be good enough for some people.

    • @UnderpantsWeevil@lemmy.world
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      221 year ago

      I have to imagine that blocking puberty has some crazy side effects.

      Sort of the joke. Puberty is what has the crazy side effects.

    • @Dasus@lemmy.world
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      1 year ago

      Discovered in 1971, and introduced for medical use in the 1980s.

      “Where can I find studies about it”?

      Have you tried perhaps, idk, a search engine? How do I have a feeling that even if I were to show you the science which agrees that they are safe medications, you’d have an “argument” in which you criticise the info without even reading it.

      People perfectly well know how to look for things online, and when they pretend not to… well, it smells fishy. Fishy, like sealions.

    • @assassin_aragorn@lemmy.world
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      261 year ago

      How long has this medical technology been in use and where can I find studies about it?

      Decades. It was there when I was a kid, so like 20 years ago. And it wasn’t new medical technology at the time.

    • @TranscendentalEmpire@lemm.ee
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      1261 year ago

      blocking puberty has some crazy side effects.

      I’m a provider at a children’s hospital. I specialize in orthopedics and rehabilitation, so I mostly deal with the musculoskeletal system. I have colleagues who would be able to provide a much better and more in depth explanation, but I will do my best.

      Even in orthopedics “hormone blockers” are used fairly frequently. For example the same drugs that people use to transition are utilized to moderate the epiphyseal fusion of growth plates. Puberty is also frequently delayed to moderate the hormone levels of juvenile cancer patients. Or even more increasingly common, to halt the symptoms of precocious puberty in young women.

      The vast majority of juveniles prescribed hormones to delay puberty are for non gender affirming care like cancer. The problem with moderating what medical providers can and can’t treat is that you are assuming you know more about medicine than the a person who went to medical school.

      You may be trying to protect kids, but what ends up happening is an interference of medical care, and usually not the type you intended. If hormone drugs become more monitored, providers may be hesitant, or have a more difficult brine prescribing it.

      The dangers of delaying puberty are very small, when you stop the prescription puberty begins again. Usually the only side effect is excessive growth due to a delay if epiphyseal fusion. In regards to gender affirming care, I will remind people that their providers are looking at total outcomes. Meaning they are factoring in things like the higher potentiality of self harm and suicide.

        • @TranscendentalEmpire@lemm.ee
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          161 year ago

          Provider is actually the preferred terminology in most hospitals nowadays. It helps transition away from physicians being the “captain of the ship” to a more team based medical approach.

          It also helps boost patient confidence in the entire medical team, especially in places like where I work, where there are a lot of residents and PAs doing the bulk of the patient care.

            • @mightyfoolish@lemmy.world
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              21 year ago

              I know therapists and other medical professionals. There is a push to let people see non physicians directly instead of needing a physician to refer you to the person who can obviously help you more.

            • @TranscendentalEmpire@lemm.ee
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              141 year ago

              Lol, Idk. Do people go to medical school for the title, or to actually help people?

              I like the team approach, and I think referring to everyone as a provider is especially good for my residents, some of which will occasionally think they know more than a PA-C who’s been here for 30 years, just because they don’t have an MD after their name.

              The only doctors that care about being called doctor are residents who think too highly of themselves, or the dinosaurs who hate patient care and only got into the field for the prestige.

              • @DarkroomDoc@lemmy.sdf.org
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                -81 year ago

                You can feel about it however you’d like, but the term provider was purposely used to justify different care without patients being aware.

                It’s not a matter of a 30 year PA vs a resident, experience certainly matters. But I take issue when you claim medical knowledge because you’re a “provider”, and especially because you work in a pediatric hospital. The role of a pediatric endocrinologist and an ortho PA almost don’t overlap, and the background schooling almost don’t either.

                That’s not to say I’m particularly qualified either (it’s outside my specialty) but you infer that you’re qualified to comment when you and I both know, frankly, you’re not.

                • @TranscendentalEmpire@lemm.ee
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                  71 year ago

                  used to justify different care without patients being aware.

                  Lol, you really think a PA is going to provide different care than an MD? What, an MD is going to prescribe PT and bracing when a PA is going to … chop their leg off?

                  But I take issue when you claim medical knowledge because you’re a “provider”, and especially because you work in a pediatric hospital.

                  Did I not predicate my statement with my lack of speciality? What exactly did I say that was false? If you have problems with the information I stated then say so. But, if all you are doing is appealing to an entirely assumed authority, go kick rocks.

                  The role of a pediatric endocrinologist and an ortho PA almost don’t overlap, and the background schooling almost don’t either.

                  What? I mean endocrinology doesn’t refer the majority of our patients, but it’s a significant amount… Also, the only information I gave over endocrinology, directly pertains to my field.

                  but you infer that you’re qualified to comment when you and I both know, frankly, you’re not.

                  Lol, I have no idea how qualified you are, and you have no idea what my qualifications are. However, based on your statement I highly doubt you actually work in patient care. Seems like you’re pretending to be a character of a doctor from a 00’s medical drama.

    • @Lyrl@lemm.ee
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      191 year ago

      It reduces bone density. Not to unhealthy levels in teens, but there are concerns the lower baseline will increase osteoporosis risk when the patients get to old age.

      They can also only be used for a couple of years. Some non-binary people want to be on them permanently, but doctors won’t prescribe that. Some kids want more time to decide, and unfortunately there isn’t anything safe to use through the full teenage years.

    • @Omniraptor@lemm.ee
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      1 year ago

      Precocious puberty has been a thing forever and the first medications for delaying it by regulating hormones have been around since the 1980s. I think that should be the jumping off point for research. However afaik the same sorts of drugs are also commonly used to treat cancer in adults.

      Here is an article about their use in treating trans people with links to various studies https://transfemscience.org/articles/puberty-blockers/

    • @ynthrepic@lemmy.world
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      The side effects and risks are worth it when you only get one shot at puberty. If you don’t transition as a pre-pubescent teenager, you will never “pass” as well, especially as a transwoman.

      A really good example of how successful you can be if you’re early is Corey Maison. There are cases of transition regret of course, but they’re still a very small percentage of the total, and that percentage is reduced by puberty blockers giving young people more time to figure out themselves and their own bodies, and to make the choice that’s right for them.

      • @VR20X6@slrpnk.net
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        Yeah, that’s the gravity of things that people don’t seem to understand. Yes, there can be unwanted side effects from puberty blockers, but they are relatively minor. On the other hand, one possible side effect for people that are willing to brave those puberty blocker side effects but aren’t allowed to do so is suicide. This is unfortunately often life or death.

    • @fidodo@lemmy.world
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      21 year ago

      There’s some studies that found that bone density could be affected, but considering the suicide rate of trans people I’m going to say that’s a tiny sacrifice for the assurance that you can have the body your brain wants to be in.

  • @Korne127@lemmy.world
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    801 year ago

    Best interest of the child my ass. I knew and know so many trans kids that suffer(ed) so much from such awful transphobic laws.
    That’s just purely disgusting and will have horrible consequences for so many people. I am so sorry for every trans kid in England that suffers from this. :(

    • @UnderpantsWeevil@lemmy.world
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      341 year ago

      40 years of Hollyweird / Music Industry / Olympics trainer agents pumping their youngest stars full of this shit in order to squeeze an extra year or two of revenue out of them? Fine. Cool. Good. No problems detected.

      Some trans youth have a legitimate medical need for deferring puberty, while they come to terms with their gender and sexuality? Fuck you. Prohibited. Go directly to jail.

        • @Drivebyhaiku@lemmy.world
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          Honey. We know our shit and we often know it young. I had to go through puberty knowing as I was experiencing it every moment was taking me further and further into a body horror I knew I would never come to terms with. Other trans people my age are very much the same and you know what? A lot of us live with deep lifelong regrets knowing that we have less options to travel the world or exist comfortably in public because of that puberty we knew bone deep right from the get go we never wanted.

          Being trans isn’t subtle. It screams at you, gnaws at your insides how wrong everything is. Particularly when pre-puberty you are able to perfectly pass… And then every minute puberty slowly takes that away from you by inches like a slow bleeding wound until you ache to have what you know you will never effortlessly experience again.

          Ignorance fucking doomed me. Yours will do nothing but doom others.

            • @Drivebyhaiku@lemmy.world
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              Yeah… Is pushing 40 considered young now or do I have to be fucking senile before I count? Take your paternalistic shit and cram it right back up your ass where it came from.

    • Kalkaline
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      351 year ago

      They’re going to have to pull an Alabama and do some matching legal and mental gymnastics.

    • @Socsa@sh.itjust.works
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      91 year ago

      You see, every other problem in the UK has been solved, so now all they have left is fucking with people who just want to be happy in their own body.

      • @floofloof@lemmy.ca
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        1 year ago

        Right-wingers pick on minorities precisely because they have no plans for how to improve life for people in general, and in fact not the slightest interest in doing so. If they were honest about that, no one would vote for them, so they have to invent scapegoats and distractions. Somehow it’s easy to persuade a lot of people that some entirely made up problem is the most urgent, such as some minority coming to destroy their “way of life”, and thereby distract them from all the actual problems you have caused for them.

        Right wing politics is always privileged sociopaths duping the gullible and ignorant.

  • @harderian729@lemmy.world
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    61 year ago

    I wonder what the statistics are of “trans youth” figuring out they’re actually not trans as they get older.

    • @Betch@lemmy.world
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      81 year ago

      Basically non-existant but of course when it does happen it gets repeated over and over again. The main reason why anybody detransitions is because of how they get treated during their transition.

    • @chetradley@lemmy.world
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      171 year ago

      I’m assuming you’re asking in good faith. I found this type of question to be especially controversial due to the legislation against gender-affirming care, especially puberty blockers. In researching further:

      As others have stated, cases where permanent gender-affirming care was given, such as HRT (hormone therapy) and GRS (genital reconfiguration surgery), instances of regret are incredibly rare, and almost always predicated by lack of support for the individual. They are far outnumbered by instances of trans people undergoing puberty incompatible with their gender, which is itself damaging and irreversible.

      The type of care discussed in this article, GnRH (puberty blockers), has been shown to not have long term consequences, and is only used to delay puberty and the potential long term effects, giving them enough time to make an informed decision about their transition. From the Mayo Clinic:

      GnRH analogues don’t cause permanent physical changes. Instead, they pause puberty. That offers a chance to explore gender identity. It also gives youth and their families time to plan for the psychological, medical, developmental, social and legal issues that may lie ahead…

      When a person stops taking GnRH analogues, puberty starts again.

    • @thesporkeffect@lemmy.world
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      201 year ago

      I was going to downvote and move on, but instead…

      I have family and friends that are trans, so I have been able to kind of follow their outcomes over the years.

      1. Human gender identity and sexuality does seem to fluctuate somewhat, but it doesn’t seem to me to be random. Some people fully identify as one gender but like to perform as a different one. Other people don’t vary at all. In cases where people “change their mind”, it’s usually because they get discouraged about being able to successfully transition, or they experience severe harassment/workplace discrimination. Just in my anecdotal experience, it’s never because they just randomly decide they no longer want to be trans

      2. No one is getting permanent gender affirmation treatment until they are old enough to know and have been in discussions with doctors for years. I’m sure there are exceptions where some poor 5 year olds parent(s) treated them without medical oversight but it’s not common and no one wants this.

    • @Ultraviolet@lemmy.world
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      161 year ago

      Extremely uncommon. But on the off chance it happens, they just stop taking the puberty blockers and everything proceeds as normal.

            • Neuromancer
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              -261 year ago

              It obvious you’re not trying to have serious conversation since you didn’t read the study and are conflating detransitioning with people who outgrow it. If you don’t understand a topic well enough to talk about it then don’t. I’m done

          • @FluffyPotato@lemm.ee
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            151 year ago

            Not in that study. The link you provided only has the abstract but it’s not even about how common detransitioning is.

            It has a sample size of 25 so it couldn’t even draw an average with that but according to the study it’s goal seems to be to document the motives for transitioning for people who go on to transition and the ones who don’t.

        • @chetradley@lemmy.world
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          51 year ago

          It’s also the worst type of wrong: the type that has the potential to seriously harm people. Hopefully they retract it instead of continuing to double down.

    • @Adanisi@lemmy.zip
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      61 year ago

      “Cult of trans”

      Who’s the leader? What’s the goal?

      Also, citing the Torygraph rag instead of actual sources isn’t a good look.

  • @dugmeup@lemmy.world
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    921 year ago

    Right wing conservatives can go pound sand. Talk about the government pushing itself between a doctor and patient care.

    A landmark bullshit decision.

    • @whotookkarl@lemmy.world
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      151 year ago

      Do you think it would be important to understand the clinical requirements, outcomes, and medical consensus of the previous policy vs a blanket ban before endorsing a ban? Isn’t the point of blockers to slow development so informed consent about transitioning can be made?

    • @PlantDadManGuy@lemmy.world
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      -61 year ago

      You’re not going to get any sympathy here, but for what it’s worth I agree with you. Some children may be entirely convinced that they know exactly what they want, and two years later they may find out they were completely wrong. I’m a trans ally, but I think children should require the explicit informed consent of their parents for any and all medical treatments including hormone therapy.

      • @5too@lemmy.world
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        71 year ago

        As I understand it, the rate of post-hormone regret for these kids is extremely low. Like, single or double digits low.

        • @Adanisi@lemmy.zip
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          51 year ago

          And to add to that, this isn’t hormone replacement therapy. This is a temporary pause on your hormones.

            • @Adanisi@lemmy.zip
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              01 year ago

              Okay then, but that doesn’t really help your position either way.

              Gillick competency be damned.

      • @frostysauce@lemmy.world
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        91 year ago

        Good thing puberty blockers are completely reversible should the child end up being wrong. But if they are not wrong they are spared living through their body changing further into the opposite of their gender.

    • @WormFood@lemmy.world
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      161 year ago

      this is why i haven’t taken my kid to get his supposed ‘broken leg’ fixed. sorry kiddo but i have thoroughly inspected it and determined that the bone angles are within tolerance